Since February 28, US-Israeli strikes on Iran have killed several senior political and military figures, hitting the core of the Islamic Republic’s leadership in a war that has spread across the Middle East, disrupting energy markets and shipping routes.The attacks, launched in the midst of nuclear talks between Washington and Tehran mediated by Oman, are the most significant assault on Iran in decades, following a long-running shadow conflict and a 12-day war in June 2025.For all the latest headlines, follow our Google News channel online or via the app.Below are some of the most prominent figures killed:Supreme LeaderAli Khamenei, who as Iran’s Supreme Leader since 1989 built an iron grip over the Islamic Republic while entrenching hostility towards the US and Israel, was killed aged 86 in a US-Israeli air strike on his compound in Tehran on February 28.His more than three-decade rule was marked by the consolidation of power through the security apparatus, and the expansion of Iran’s