Scouted/The Daily Beast/Amazon. Scouted selects products independently. If you purchase something from our posts, we may earn a small commission. From snail mucin to exosomes, it’s hard to keep up with the ever-growing list of buzzy (and often unconventional) ingredients that promise to deliver a glowing complexion, erase signs of sun damage, and target sagging skin. PDRN (polydeoxyribonucleotide) is the latest ingredient in the skincare spotlight. Typically derived from salmon or sturgeon sperm, PDRN started gaining traction in 2025, thanks in large part to the Kardashians. Kim Kardashian revealed she got a “salmon sperm facials,” while her mother, Kris Jenner, has publicly praised Rejuran’s PDRN-powered skincare line . Other celebs, including Jennifer Aniston and Miley Cyrus , have also admitted to trying the unusual beauty treatment. Read more at The Daily Beast.