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Best-selling queer novel The Charm Offensive getting major adaptation

Best-selling queer novel The Charm Offensive getting major adaptation

Alison Cochrun’s best-selling queer romance novel The Charm Offensive is set for a major movie adaptation, starring Atypical actor Nik Dodani.  Released in 2021, the book follows Dev Deshpande, a high-flying producer on a romance reality show, who is famed for creating success stories despite his own faltering love life. When disgraced, cold and socially […] The post Best-selling queer novel The Charm Offensive getting major adaptation appeared first on PinkNews | Latest lesbian, gay, bi and trans news | LGBTQ+ news .

A Brazilian Plant May Help Treat, And Even Protect Against, Arthritis

A Brazilian Plant May Help Treat, And Even Protect Against, Arthritis

New research published in the Journal of Ethnopharmacology has suggested that Joseph’s coat, a plant used in traditional Brazilian medicine, appears to have anti-inflammatory and pain-relieving properties. It could be useful for treating and even protecting arthritic joints, the paper says. The plant grows along Brazil’s coastline, and has historically been used to treat inflammation, microbial infections, and parasitic diseases, the paper reads. But this paper adds more scientific evidence to these uses. Why can Joseph’s coat help with arthritis? In this paper, scientists first looked at the chemical makeup of the plant. They identified the bioactive parts of Joseph’s coat, or isolated the compounds which seemed to have the most medicinal effects. Then, they found that an ethanolic extract made from the plant helped to reduce inflammation in laboratory animals. Arthritis is linked to inflammation in affected joints , which can cause pain, stiffness, and reduced movement. That’s why steroid injections are sometimes used as a short-term way to manage arthritis pain. “In the experimental models, we observed reduced oedema, improved joint parameters, and modulation of inflammatory mediators, suggesting antioxidant and tissue-protective actions,” associate professor Arielle Cristina Arena, who co-authored the study, said . Additionally, the extract they gave to animals appeared to be safe. The researchers think this could be a strong enough basis on which to begin preclinical research on how Joseph’s coat could affect humans. Does that mean it’ll definitely treat arthritis in humans? Not definitely. Though the paper said an ethanolic extract made from Joseph’s coat “exhibits significant anti-inflammatory, analgesic, and anti-arthritic activities, supporting its traditional use and potential as a safe ethnopharmacological resource,” this was only shown in animals. Much more research will be needed to see whether it works in humans and how much, in what form, and at what dose it could help us. “Further studies should focus on compound isolation, chronic toxicity, and pharmacokinetics,” the study ended. Related... This 'Tart' Fruit Is Linked To Improved Sleep And Arthritis Study Reveals This 1 Exercise Can Reduce Arthritis And Knee Pain We're Millennials And We Have Rheumatoid Arthritis – This Is What It Feels Like

Extreme rainfall inundates South Africa and Mozambique

Extreme rainfall inundates South Africa and Mozambique

Flood warning raised to highest level with roads washed away and rain forcing evacuation of Kruger national park Large areas of north-eastern South Africa and neighbouring Mozambique have been inundated for several days with exceptionally heavy rainfall. Some locations in South Africa recorded hundreds of millimetres of rain over the weekend, such as Graskop in Mpumalanga, where 113mm fell in a 24-hour period, and Phalaborwa, which recorded about 85mm of rainfall. Rain has continued to fall across the region since the weekend. The deluge has been driven by a slow-moving cut-off low pressure system that has remained anchored over the region, repeatedly drawing in moisture and triggering intense downpours. Further heavy rainfall is expected on Friday and over the weekend. Maputo, Mozambique’s capital, could expect daily rainfall totals to exceed 200mm by the end of Friday, while western parts of South Africa and north-western Eswatini may record more than 100mm, though exact totals remain uncertain at this stage. Continue reading...